虚拟现实正念疗法改善共病重度焦虑的偏执型精神分裂症患者症状 1 例 ——案例报告与机制探讨
摘要
包括：在药物治疗效果不佳并出现不良反应后，采用 VR-MBCT 进行系统干预，共 16 次，每周 2 次，每次 35 分钟。通过
沉浸式虚拟环境进行正念呼吸、身体扫描、肌肉松弛等训练，并结合焦虑自评量表（SAS）、汉密尔顿焦虑量表（HAMA）、
正念注意觉知量表（MAAS）、匹兹堡睡眠质量指数（PSQI）及震颤评定（TRS）进行阶段性评估。结果显示，干预 2 周
后患者焦虑症状及震颤明显缓解，4 周后基本控制，8 周后各项评分恢复至正常范围，睡眠质量显著改善。出院后一周随访
未见复发。本案例提示，VR-MBCT 可作为中老年重度焦虑患者，特别是对药物治疗不耐受或传统心理治疗参与困难者的
一种新颖、安全且有效的非药物辅助干预选择。
关键词
全文:
PDF镜像
|参考
[1]Ge H, Liu Z, Tong Y, Huang Y, Hou X, Li M, Yan Y,
Xiao S, Li L, Zhang T, Yan J, Yu Y, Xu X, Wang Z, Xu Y, Li T,
Xu X, Wang L, Yin H, Xu G. Prevalence and correlates of anxiety
disorders and depressive disorders among older adults with non-
communicable diseases: results from China Mental Health Survey.
Front Psychiatry. 2025 Aug 8;16:1626540.
[2] 王 紫 薇 , 张 函 , 夏 叶 , 等 . 正 念 疗 法 在 焦 虑 障
碍 治 疗 中 的 应 用 和 研 究 进 展 [J]. 神 经 损 伤 与 功 能 重
建 ,2024,19(12):774-778.
[3]Straarup NS, Renneberg HB, Farrell J, Younan R. Group
schema therapy for patients with severe anxiety disorders. J Clin
Psychol. 2022;78(8):1590-1600.
[4]Berto R.Exposure to restorative environments helps
restore attentional capacity[J].Journal of Environmental
Psychology,2005,25(3):249-259.
[5]Chen L, Yan R, Yu J. Virtual nature, real relief: how
exposure to virtual natural environments reduces anxiety, stress,
and depression in healthy adults. NPJ Digit Med. 2025 Nov
18;8(1):679. [6]Melati KBDS, Bellynda M, Yarso KY, Kusuma W,
Sudiyanto A. The Effectiveness of Mindfulness-Based Cognitive
Therapy to Improve Anxiety Symptoms and Quality of Life in
Breast Cancer Patients. Asian Pac J Cancer Prev. 2024 Sep
1;25(9):3081-3086.
[7]Wieczorek A, Schrank F, Renner KH, Wagner M.
Psychological and physiological health outcomes of virtual
reality-based mindfulness interventions: A systematic review and
evidence mapping of empirical studies. Digit Health. 2024 Oct
25;10:20552076241272604.
[8]Michela A, van Peer JM, Brammer JC, Nies A, van
Rooij MMJW, Oostenveld R, Dorrestijn W, Smit AS, Roelofs K,
Klumpers F, Granic I. Deep-Breathing Biofeedback Trainability
in a Virtual-Reality Action Game: A Single-Case Design Study
With Police Trainers. Front Psychol. 2022 Feb 10;13:806163.
[9]Lee J, Kim J, Ory MG. The impact of immersive virtual
reality meditation for depression and anxiety among inpatients with
major depressive and generalized anxiety disorders. Front Psychol.
2024 Oct 21;15:1471269.
[10]Bishay AE, Lyons AT, Habib DRS, Hughes NC, Long I,
Zargari M, Qian H, Paulo D, Summers JE, Li R, Bishay S, Terry
DP, Dawant BM, Ball TJ, Konrad PE, Englot DJ, Dhima K, Bick
SK. Effect of deep brain stimulation on nonmotor symptoms in
essential tremor. J Neurosurg. 2025 Mar 7;143(1):38-52.
[11]Pardini S, Gabrielli S, Olivetto S, Fusina F, Dianti
M, Forti S, Lancini C, Novara C. Personalized Virtual Reality
Compared With Guided Imagery for Enhancing the Impact of
Progressive Muscle Relaxation Training: Pilot Randomized
Controlled Trial. JMIR Ment Health. 2024 Jan 30;11:e48649.
[12] Diniz JL, Oliveira NMC, Coutinho JFV, Marques MB,
Pillon CB, Araújo ÍL. Purposes and characteristics of virtual
reality technologies for the elderly in the community: a scoping
review. Rev Lat Am Enfermagem. 2024 Nov 22;32:e4389.
[13]Kanyılmaz T, Topuz O, Ardıç FN, Alkan H, Öztekin SNS,
Topuz B, Ardıç F. Effectiveness of conventional versus virtual
reality-based vestibular rehabilitation exercises in elderly patients
with dizziness: a randomized controlled study with 6-month
follow-up. Braz J Otorhinolaryngol. 2022 Nov-Dec;88 Suppl
3(Suppl 3):S41-S49.
[14]Lee BM, Kim SW, Lee BJ, Won SH, Park YH, Kang CY,
Li L, Rami FZ, Chung YC. Effects and safety of virtual reality-
based mindfulness in patients with psychosis: a randomized
controlled pilot study. Schizophrenia (Heidelb). 2023 Sep
13;9(1):57.
[15]Meshkat S, Edalatkhah M, Di Luciano C, Martin J,
Kaur G, Hee Lee G, Park H, Torres A, Mazalek A, Kapralos B,
Dubrowski A, Bhat V. Virtual Reality and Stress Management: A
Systematic Review. Cureus. 2024 Jul 15;16(7):e64573.
[16]Bryant L, Stubbs P, Bailey B, Nguyen V, Bluff A, Hemsley
B. Interacting with virtual characters, objects and environments:
investigating immersive virtual reality in rehabilitation. Disabil
Rehabil Assist Technol. 2025 Jan;20(1):107-117.
[17] 董奇峰 , 郁梅 , 蒋志迪 , 等 . 虚拟现实中视觉诱发晕
动症时空多特征评价 [J]. 光学精密工程 ,2024,32(04):595-608.
[18]Wen E, Gupta C, Sasikumar P, Billinghurst M, Wilmott
J, Skow E, Dey A, Nanayakkara S. VR.net: A Real-world Dataset
for Virtual Reality Motion Sickness Research. IEEE Trans Vis
Comput Graph. 2024 May;30(5):2330-2336.
[19] 顾展滔 , 丁玎 , 陈亦婷 , 等 . 面向虚拟现实晕动症的
评估与缓解方法 [J]. 浙江大学学报 ( 理学版 ),2025,52(01):30-
37.
(13 摘要 Views, 44 PDF Downloads)
Refbacks
- 当前没有refback。